New Study Shows Depressive Symptoms Tied to Doubled Risk of Crohn’s in Women

January 17, 2013 at 9:39 pm Leave a comment

A recent study published in the January issue of Clinical Gastroenterology and Hepatology shows a link between depressive symptoms and the incidence of Crohn’s disease and UC. The following information was taken from a write up on

Researchers from Massachusetts General Hospital and Harvard Medical School collected data from 152,461 women who participated in either the Nurses’ Health Study I or II. From the data collected, a total of 170 cases of Crohn’s and 203 cases of UC were reported from this population.

“We observed that depressive symptoms are associated with a two-fold increase in risk of CD but not UC. Although both recent (within four years) and remote (baseline) assessments of depression appear to influence disease risk, the association with recent depressive symptoms appeared more prominent,” the authors write. “Our findings support the potential importance of a biopsychosocial model in the pathogenesis of CD and suggest the need for further studies on the effect of depression and stress on immune function and regulation.”

The researchers found that women with depressive symptoms within the past four years, were more than two times more likely to be diagnosed with Crohn’s disease. However, no similar link between depressive symptoms and increased risk of UC was identified.

This is an extremely interesting development. As we all know, depression and IBD can go hand-in-hand due to the physical and mental toll the diseases take on your body. However, now there is scientific evidence that actually shows that psychological factors can contribute to developing Crohn’s disease.

You can read the full study here.


Entry filed under: Mental Health. Tags: , , , , , , , .

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Brian Greenberg

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